They've practically already done that, Leo. The designs have leaned too much on the anthropomorphic side.
Anyway, I just checked the Tamagotchi Wiki for the On/Meets and the M!X and yeah, they rerelease new versions pretty consistently. I wonder if maybe they've stumped themselves on what to do next as the whole genetic mixing has carried on (pun not intended) and what can they really do but add new towns, items, characters, and basically all of that "same thing different sprite" stuff? I don't see how they could make the functions more realistic besides borrowing from the Famlitichi/V5 and maybe trying to incorporate raising a family of tamas (hopefully more interactive than the twin feature). They could potentially break away from it by having a new kind of gameplay - similar to how the Music Star/V6 centers on music and performing - but maybe they've already done that by focusing on Nanos. They could of course switch it up like the vintage models and maybe simulate raising another kind of creature, like from the sea (like the Umino/Ocean) or a new life form (like the Mothra, although a weaker example). That would be quite intriguing.
Of course, perhaps it is too early to tell and they do have something in the works. Or perhaps the global events have been becoming more and more invasive and it's not profitable due to the widespread unemployment - or it's impossible because of the gradual increase in totalitarianism. That last remark may make me sound like a nut but look at Victoria, Australia - it already is a police state. Obviously, development of anything isn't going to happen if there are broader, societal problems.